JetBrains PyCharm

JetBrains PyCharm screenshots

JetBrains PyCharm is a Python IDE for professional developers
Project Window
JetBrains PyCharm 4.0 : Project Window

Alternative downloads

JetBrains PyCharm Community Edition
It is a free Python IDE with unique code assistance and analysis.
JetBrains RubyMine
RubyMine is a powerful IDE with smart coding assistance.
Microsoft Visual Studio Ultimate 2013 Preview
It simplifies the tasks of creating, debugging and deploying apps.